Lab published research papers (sorted by year). Click on the publication link to access a PDF version

2011

Petrs-Silva H, Dinculescu A, Li Q, Deng WT, Pang JJ, Min SH, Chiodo V, Neeley AW, Govindasamy L, Bennett A, Agbandje-McKenna M, Zhong L, Li B, Jayandharan GR, Srivastava A, Lewin AS, Hauswirth WW. Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina. Mol Ther. 2011 Feb;19(2):293-301. [Epub ahead of print 2010 Nov 2] PubMed PMID: 21045809.
Petrs-Silva 2011

Sippel KH, Venkatakrishnan B, Boehlein SK, Sankaran B, Quirit JG, Govindasamy L, Agbandje-McKenna M, Goodison S, Rosser CJ, McKenna R. Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein. Proteins. 2011 Feb;79(2):528-36. PubMed PMID: 21117240; PubMed Central PMCID: PMC3017431.
Sippel 2011

Pulicherla N, Shen S, Yadav S, Debbink K, Govindasamy L, Agbandje-McKenna M, Asokan A. Engineering Liver-detargeted AAV9 Vectors for Cardiac and Musculoskeletal Gene Transfer. Mol Ther. 19(6):1070-8. [Epub ahead of print 2011 Mar 1] PubMed PMID: 21364538.
Pulicherla 2011

Bell CL, Vandenberghe LH, Bell P, Limberis MP, Gao GP, Van Vliet K, Agbandje-McKenna M, Wilson JM. 2011. The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice. J Clin Invest. 121(6):2427-35. [Epub ahead of print 2011 May 16] PubMed PMID: 21576824.
Bell 2011

Sippel, K. H., B. Venkatakrishnan, S. K. Boehlein, B. Sankaran, J. Quirit, L. Govindasamy, M. Agbandje-McKenna, S. Goodison, C. J. Rosser, R. McKenna. 2011. Insights into mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein. PROTEINS: Structure, Function, and Bioinformatics, Proteins.79:528-536.
Sippel 2011a

Weise, A., H.-P. Schneider, R. McKenna, J. W. Deitmer. 2011. Substrate-dependent Interference of carbonic anhydrases with the glutamine transporter SNAT3-induced conductance. Cell Physiol Biochem., 27:79-90.
Weise 2011

Becker, H. M., M. Klier, C. Schüler, R. McKenna, J. W. Deitmer. 2011. The intramolecular proton shuttle does not only support catalytic, but also non-catalytic function of carbonic anhydrase II. Proc Natl Acad Sci U S A. 108:3071-3076.
Becker 2011

Maupin, C. M., N. Castillo, S. Taraphder, Chingkuang Tu, R. McKenna, D. N. Silverman, G. A. Voth, 2011. Chemical rescue of enzymes: Proton transfer in mutants of human carbonic anhydrase II. J Am Chem Soc. 133:6223-6234.
Maupin 2011

Carta, F., V. Garaj, A. Maresca, J. M. Wagner, B. S. Avvaru, A. H. Robbins, A. Scozzafava, R. McKenna, C. T. Supuran. 2011. Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: solution and X-ray crystallographic studies. Bioorg Med Chem. 19:3105-3119.
Carta 2011

Hen, N., M. Bialer, B. Yagen, A. Maresca, M. Aggarwal, A. H. Robbins, R. McKenna, A. Scozzafava, C. T. Supuran. 2011. Benzenesulfonamides incorporating lipophilic moieties with anticonvulsant activity: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII and XIV. J Med Chem. 54:3977-3981.
Hen 2011

Biswas, S., M. Aggarwal, Ö. Güzel, A. Scozzafava, R. McKenna, C. T. Supuran. 2011. Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms. Bioorg Med Chem. 19: 3732-3738.
Biswas 2011

Sippel, K. H., A. Stander, C.-K. Tu, B. Venkatakrishnan, A. H. Robbins, M. Agbandje-McKenna, F. Joubert, A. M. Joubert, R. McKenna. 2011. Characterization of Carbonic Anhydrase Isozyme specific inhibition by Sulfamated 2-Ethylestra compounds. Letters in Drug Design & Discovery. 8: 678-684.
Sippel 2011b

Schueler C., H. M. Becker, R. McKenna, J. W. Deitmer. 2011. Transport activity of the sodium bicarbonate cotransporter NBCe1 is enhanced by different isoforms of carbonic anhydrase. PLoS One. 6 (11):e27167.
Schueler 2011

Nam, H. J. , B. L. Gurda, R. McKenna, M. Potter, B. Byrne, M. Salganik, N. Muzyczka, M. Agbandje-McKenna. 2011. Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J. Virol. 85:11791-11799.
Nam 2011

Fisher, Z., A. Y. Kovalevsky, M. Mustyakimov, D. N. Silverman, R. McKenna, P. Langan. 2011. Neutron structure of human carbonic anhydrase II: a hydrogen-bonded water network "switch" is observed between pH 7.8 and 10.0. Biochemistry. 50:9421-9423.
Fisher 2011

S. H., Subramony, T. Ashizawa, L. Langford, R. McKenna, B. S. Avvaru, V. Vedanarayanan. 2011. Confirmation of the differential phenotypic effect of serine and aspartate at codon 41 of the SOD 1 gene. Muscle and Nerve. 44:499-502.
Subramony 2011

Paschall, C. O., J. A. Thompson, W. R. Marzahn, A. Chiraniya, J. N. Hayner, M. O'Donnell, A. H. Robbins, R. McKenna, L. B. Bloom. 2011. The Escherichia coli clamp loader can actively pry open the ß-sliding clamp. J Biol Chem. 286:42704-42714.
Paschall 2011

Mikulski, R., J. F. Domsic, G. Ling, C. K. Tu, A. H. Robbins, D. N. Silverman, R. McKenna. 2011. Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5. Arch Biochem Biophys. 516:97-102.
Mikulski 2011

Harbison CE, Weichert WS, Gurda BL, Chiorini JA, Agbandje-McKenna M, Parrish CR. 2011. Examining the cross-reactivity and neutralization mechanisms of a panel of monoclonal antibodies against Adeno-associated virus serotypes 1 and 5. J Gen Virol. 2012 Feb;93(Pt 2):347-55. Epub 2011 Nov 9. PubMed PMID: 22071509.
Harbison 2011

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